Stereoselective Mannich Reactions in the Synthesis of Enantiopure Piperidine Alkaloids and Derivatives - Rootselaar - European Journal of Organic Chemistry - Wiley Online Library
Mannich Reaction - Mechanism and Applications - YouTube
Mannich Reaction Mechanism - Reaction Details and Applications
SOLVED: The Mannich reaction is a three-component condensation reaction that proceeds through the following steps: Imine or iminium ion formation between the amine and the aldehyde. 2 Enolization of the other ketone (